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Overview

Uniprot IDA0A480LAI1
Protein NameRNA-binding protein 10
Gene NameRBM10
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
387 HGYLKGAKGPGITGT
570 KKEKHKTKTAQQIAK
748 RAAERREKYGIPEPP

Function

Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A). May bind to specific miRNA hairpins

Protein Sequence

10 MEYERRGGRG 20 DRTGRYGAAD 30 RSQDDGGENR 40 SRDHDYRDMD 50 YRSYPREYGG 60 QEGKHDYDDS 70 SEEQSAEIRG 80 QLQSHGVQAR 90 EVRLMRNKSS 100 GQSRGFAFVE 110 FSHLQDATRW 120 MEANQHSLNI 130 LGQKVSMHYS 140 DPKPKINEDW 150 LCNKCGVQNF 160 KRREKCFKCG 170 VPKSEAEQKL 180 PLGARLDQQT 190 LPLGGRELSQ 200 GLLPLPQPYQ 210 AQGVLASQAL 220 SQGSEPSSEN 230 ANDTIILRNL 240 NPHSTMDSIL 250 GALAPYAVLS 260 SSNVRVIKDK 270 QTQLNRGFAF 280 IQLSTIVEAA 290 QLLQILQALH 300 PPLTIDGKTI 310 NVEFAKGSKR 320 DMASNEGSRI 330 NAASVASTAI 340 AAAQWAISQA 350 SQGGEGAWAT 360 PEEPPVDYSY 370 YQQDEGYGGS 380 QGTESSLYAH 390 GYLKGAKGPG 400 ITGTKGDPSG 410 AGPEASLEPG 420 ADSVSLQAFS 430 RAQPGATPGV 440 YQQSAAEASG 450 GQGAATNSQS 460 YTIMSPAVLK 470 SELQSPTHPS 480 SSLPPATSPT 490 AQESYSQYPV 500 PDVSTYQYDE 510 TSGYYYDPQT 520 GLYYDPNSQY 530 YYNAQSQQYL 540 YWDGERRTYV 550 PALEQSADGH 560 KETGAPSKEG 570 KEKKEKHKTK 580 TAQQIAKDME 590 RWARSLNKQK 600 ENFKNSFQPI 610 SSLRDDERRE 620 SATADAGYAI 630 LEKKGALAER 640 QHTSMDLPKL 650 ASDDRPSPPR 660 GLVAAYSGES 670 DSEEEQERGG 680 PEREEKLTDW 690 QKLACLLCRR 700 QFPSKEALIR 710 HQQLSGLHKQ 720 NLEIHRRAHL 730 SENELEALEK 740 NDMEQMKYRD 750 RAAERREKYG 760 IPEPPEPKRR 770 KYGGMSAASV 780 DFEQPTRDGL 790 GSDNIGSRML 800 QAMGWKEGSG 810 LGRKKQGIVT 820 PIEAQTRVRG 830 SGLGARGSSY 840 GVTSTESYKE 850 TLHKTMVTRF NEAQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0008270 zinc ion binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.