Search Results
Overview
| Uniprot ID | A0A480LC98 |
|---|---|
| Protein Name | Mitochondrial import inner membrane translocase subunit TIM50 |
| Gene Name | TIMM50 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 252 | RVVVVDCKKEAFRLQ |
| 66 | SEGPSYAKKVALWLA |
Function
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo
Protein Sequence
10
MAASAGLFLR
20
LRSGLLQGAR
30
GLCARLATAP
40
PRAPDQTAEI
50
GSRAGTKVQV
60
QGPQQQRSSE
70
GPSYAKKVAL
80
WLAGLLGAGG
90
TVSIVYIFGN
100
NSVDENGAKI
110
PDEFDNDPIL
120
VQQLRRTYKY
130
FKDYRQMIIE
140
PTSPCLLPDP
150
LREPYYQPPY
160
TLVLELTGVL
170
LHPEWSLATG
180
WRFKKRPGIE
190
TLFQQLAPLY
200
EIVIFTSETG
210
MTAFPLIDSV
220
DPHGFISYRL
230
FRDATRYMDG
240
HHVKDISCLN
250
RDPARVVVVD
260
CKKEAFRLQP
270
YNGVALRPWD
280
GNSDDRVLLD
290
LSAFLKTIAL
300
NGVEDVRTVL
310
EHYALEEDPL
320
EAFKQRQSRL
330
EQEEQQRLAE
340
LSKSSKQNLF
350
FGSLTSRLWP
RSKQP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005744 | TIM23 mitochondrial import inner membrane translocase complex |
| Molecular Function | GO:0140608 | cysteine-type endopeptidase activator activity |
| Molecular Function | GO:0005134 | interleukin-2 receptor binding |
| Molecular Function | GO:0004722 | protein serine/threonine phosphatase activity |
| Molecular Function | GO:0004725 | protein tyrosine phosphatase activity |
| Molecular Function | GO:0043021 | ribonucleoprotein complex binding |
| Biological Process | GO:0007006 | mitochondrial membrane organization |
| Biological Process | GO:0030150 | protein import into mitochondrial matrix |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.