Search Results
Overview
| Uniprot ID | A0A480PU90 |
|---|---|
| Protein Name | Transcription initiation factor IIA subunit 2 |
| Gene Name | GTF2A2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 94 | LIKVDKVKIVACDGK |
Function
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity
Protein Sequence
10
MAYQLYRNTT
20
LGNSLQESLD
30
ELIQSQQITP
40
QLALQVLLQF
50
DKAINSALAQ
60
RVRNRVNFRG
70
SLNTYRFCDN
80
VWTFVLNDVE
90
FREVTELIKV
100
DKVKIVACDG
KNTGSNTTE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005672 | transcription factor TFIIA complex |
| Cellular Component | GO:0005669 | transcription factor TFIID complex |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0016251 | RNA polymerase II general transcription initiation factor activity |
| Molecular Function | GO:0001091 | RNA polymerase II general transcription initiation factor binding |
| Molecular Function | GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding |
| Molecular Function | GO:0017025 | TBP-class protein binding |
| Molecular Function | GO:0003743 | translation initiation factor activity |
| Biological Process | GO:0060261 | positive regulation of transcription initiation by RNA polymerase II |
| Biological Process | GO:0051123 | RNA polymerase II preinitiation complex assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.