Search Results
Overview
| Uniprot ID | A0A480SJI2 |
|---|---|
| Protein Name | Spermidine synthase |
| Gene Name | SRM |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 269 | PVQLLTQKQVEQRQL |
| 96 | CSHPNPRKVLIIGGG |
Function
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine
Protein Sequence
10
MEPGPDGPAA
20
PGPAAIREGW
30
FHETCSLWPG
40
QALSLQVEQL
50
LHHQRSRYQD
60
ILVFRSKSYG
70
NVLVLDGVIQ
80
CTERDEFSYQ
90
EMIANLPLCS
100
HPNPRKVLII
110
GGGDGGVLRE
120
VVKHPAVESV
130
VQCEIDEDVI
140
QVSKKFLPGM
150
AVSYSSSKLT
160
LHVGDGFEFM
170
KQNQDAFDVI
180
ITDSSDPMGP
190
AESLFKESYY
200
QLMKTALKEE
210
GILCCQGECQ
220
WLHLDLIKEM
230
RQFCKSLFPV
240
VDYAYCTIPT
250
YPSGQIGFML
260
CSKNPSTNFR
270
EPVQLLTQKQ
280
VEQRQLRYYN
290
SDVHRAAFVL
300
PEFARKALND
AD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0004766 | spermidine synthase activity |
| Biological Process | GO:0008295 | spermidine biosynthetic process |
| Biological Process | GO:0006597 | spermine biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.