Search Results
Overview
| Uniprot ID | A0A480SUV6 |
|---|---|
| Protein Name | Ethanolamine-phosphate cytidylyltransferase |
| Gene Name | PCYT2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | RDTYEEVKQAGRYRE |
| 326 | SDPYEEPKRRGIFCQ |
Function
Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway. Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis
Protein Sequence
10
MIRNGHETAG
20
GAERPGPGGR
30
RPVRVWCDGC
40
YDMVHYGHSN
50
QLRQARAMGD
60
HLIVGVHTDE
70
EISKHKGPPV
80
FTQEERYRMV
90
QAIKWVDEVV
100
PAAPYVTTLE
110
TLDKYGCDFC
120
VHGNDITLTV
130
DGRDTYEEVK
140
QAGRYRECKR
150
TQGVSTTDLV
160
GRMLLVTKAH
170
HSSQEMPSEY
180
REYADSFGKG
190
PGGRNPWTGV
200
SQFLQTSQKI
210
IQFASGKEPQ
220
PGETVVYVAG
230
AFDLFHIGHV
240
DFLEKVHGLA
250
ERPYVIAGLH
260
FDQEVNRYKG
270
KNYPIMNLHE
280
RTLSVLACRY
290
VSEVVIGAPY
300
SVTAELLDHF
310
KVDLVCHGKT
320
EIVADRDGSD
330
PYEEPKRRGI
340
FCQISSGNDL
350
TTDLIVQRII
360
KNRLEYEARN
370
QKKEAKELAF
380
LEAMRQQEVR
PEGESDCDF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity |
| Biological Process | GO:0006646 | phosphatidylethanolamine biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.