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Overview

Uniprot ID	A0A480TQM2
Protein Name	Sec1 family domain-containing protein 1
Gene Name	SCFD1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
314	RPKRKNKKSYDLTPV
430	YEEKIMSKTTLDKSL

Function

Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi

Protein Sequence

10 MVGVKMAAAA 20 AASIRERQTV 30 ALKRMLNFNV 40 PHVKNSAGEP 50 VWKVLIYDRF 60 GQDIISPLLS 70 VKELRDMGIT 80 LHLLLHSDRD 90 PIPDVPAVYF 100 VMPTEENIDR 110 LCQDLRNQLY 120 ESYYLNFISA 130 ISRSKLEDIA 140 NAALAASAVT 150 QVAKVFDQYL 160 NFITLEDDMF 170 VLCNQNKEIV 180 SYRAINRTDI 190 TDTEMETVMD 200 TIVDSLFCFF 210 VTLGAVPIIR 220 CSRGTAAEMV 230 AVKLDKKLRE 240 NLRDARNSLF 250 TGDTLGAGQF 260 SFQRPLLVLV 270 DRNIDLATPL 280 HHTWTYQALV 290 HDVLDFHLNR 300 VNLEESSGTE 310 TSPAGARPKR 320 KNKKSYDLTP 330 VDKFWQKHKG 340 SPFPEVAESV 350 QQELESYRAQ 360 EDEVKRLKSI 370 MGLEGEDEGA 380 ISMLSDNTAK 390 LTSAVSSLPE 400 LLEKKRLIDL 410 HTNVATAVLE 420 HIKARKLDVY 430 FEYEEKIMSK 440 TTLDKSLLDI 450 ISDPDAGTPE 460 DKMRLFLIYY 470 ISAQQAPSEA 480 DLEQYKKALT 490 DAGCNLNPLQ 500 YIKQWKAFAK 510 MASAPASYGN 520 TTTKPMGLLS 530 RVMNTGSQFV 540 MEGVKNLVLK 550 QQNLPVTRIL 560 DNLMEMKSNP 570 ETDDYRYFDP 580 KMLRGNDSSV 590 PRNKNPFQEA 600 IVFVVGGGNY 610 IEYQNLVDYI 620 KGKQGKHILY 630 GCSELFNATQ 640 FIKQLSQLGQ K

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0032580	Golgi cisterna membrane
Biological Process	GO:0015031	protein transport
Biological Process	GO:0016192	vesicle-mediated transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.