Search Results
Overview
| Uniprot ID | A0A480VIE8 |
|---|---|
| Protein Name | Transcription elongation factor SPT4 |
| Gene Name | SUPT4H1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 8 | MALETVPKDLRHLRA |
| 81 | WQRVSNFKPGVYAVS |
Function
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II
Protein Sequence
10
MALETVPKDL
20
RHLRACLLCS
30
LVKTIDQFEY
40
DGCDNCDAYL
50
QMKGNREMVY
60
DCTSSSFDGI
70
IAMMSPEDSW
80
VSKWQRVSNF
90
KPGVYAVSVT
100
GRLPQGIVRE
110
LKSRGVAYKS
RDTAIKT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0032044 | DSIF complex |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0000993 | RNA polymerase II complex binding |
| Molecular Function | GO:0140870 | RNA polymerase inhibitor activity |
| Molecular Function | GO:0003746 | translation elongation factor activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0032785 | negative regulation of DNA-templated transcription, elongation |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0032786 | positive regulation of DNA-templated transcription, elongation |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0034243 | regulation of transcription elongation by RNA polymerase II |
| Biological Process | GO:0006368 | transcription elongation by RNA polymerase II |
| Biological Process | GO:0140673 | transcription elongation-coupled chromatin remodeling |
| Biological Process | GO:0160239 | transcription pausing by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.