Search Results
Overview
| Uniprot ID | A0A481C216 |
|---|---|
| Protein Name | RuvB-like helicase |
| Gene Name | RUVBL2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 186 | IESLTKDKVQAGDVI |
| 234 | CPDGELQKRKEVVHT |
| 279 | VREQINAKVAEWREE |
| 365 | STSPYSEKDTKQILR |
| 368 | PYSEKDTKQILRIRC |
| 417 | SLVCRKRKGTEVQVD |
Function
Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding
Protein Sequence
10
MTTVTATTKV
20
PEIRDVTRIE
30
RIGAHSHIRG
40
LGLDDALEPR
50
QASQGMVGQL
60
AARRAAGVVL
70
EMIREGKIAG
80
RAVLIAGQPG
90
TGKTAIAMGM
100
AQALGPDTPF
110
TAIAGSEIFS
120
LEMSKTEALT
130
QAFRRSIGVR
140
IKEETEIIEG
150
EVVEIQIDRP
160
ATGTGSKVGK
170
LTLKTTEMET
180
IYDLGTKMIE
190
SLTKDKVQAG
200
DVITIDKATG
210
KISKLGRSFT
220
RARDYDAMGS
230
QTKFVQCPDG
240
ELQKRKEVVH
250
TVSLHEIDVI
260
NSRTQGFLAL
270
FSGDTGEIKS
280
EVREQINAKV
290
AEWREEGKAE
300
IIPGVLFIDE
310
VHMLDIESFS
320
FLNRALESDM
330
APVLIMATNR
340
GITRIRGTSY
350
QSPHGIPIDL
360
LDRLLIVSTS
370
PYSEKDTKQI
380
LRIRCEEEDV
390
EMSEDAYTVL
400
TRIGLETSLR
410
YAIQLITAAS
420
LVCRKRKGTE
430
VQVDDIKRVY
440
SLFLDESRST
450
QYMKEYQDAF
460
LFNELKGETM
DTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0120293 | dynein axonemal particle |
| Cellular Component | GO:0031011 | Ino80 complex |
| Cellular Component | GO:0035267 | NuA4 histone acetyltransferase complex |
| Cellular Component | GO:0016363 | nuclear matrix |
| Cellular Component | GO:0097255 | R2TP complex |
| Cellular Component | GO:0000812 | Swr1 complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003678 | DNA helicase activity |
| Molecular Function | GO:0140296 | general transcription initiation factor binding |
| Molecular Function | GO:0016787 | hydrolase activity |
| Biological Process | GO:0000492 | box C/D snoRNP assembly |
| Biological Process | GO:0006338 | chromatin remodeling |
| Biological Process | GO:0006310 | DNA recombination |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045739 | positive regulation of DNA repair |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.