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Overview

Uniprot IDA0A4X1SH59
Protein NameProtein transport protein Sec61 subunit beta
Gene NameSEC61B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
20 SSGRSPSKAVAARAA
35 GSTVRQRKNASCGTR

Function

Necessary for protein translocation in the endoplasmic reticulum

Protein Sequence

10 MPGPTPSGTN 20 VGSSGRSPSK 30 AVAARAAGST 40 VRQRKNASCG 50 TRSAGRTTSA 60 GTGGMWRFYT 70 EDSPGLKVGP 80 VPVLVMSLLF 90 IASVFMLHIW GKYTRS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016020 membrane
Cellular Component GO:0005784 Sec61 translocon complex
Molecular Function GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process GO:0031204 post-translational protein targeting to membrane, translocation
Biological Process GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.