Search Results
Overview
| Uniprot ID | A0A4X1SIX5 |
|---|---|
| Protein Name | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
| Gene Name | DUT |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | TQVISPSKRARPAEE |
| 40 | EHATAPTKGSERAAG |
Function
Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
Protein Sequence
10
MPCSQETQVI
20
SPSKRARPAE
30
ESRKRLRFAR
40
LSEHATAPTK
50
GSERAAGYDL
60
YSAYDYTVLP
70
MEKAIVKTDI
80
QIALPSGCYG
90
RVAPRSGLAA
100
KHFIDVGAGV
110
IDEDYRGNVG
120
VVLFNFGKEK
130
FEGMLTTLSH
ISAVCFLNN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0006226 | dUMP biosynthetic process |
| Molecular Function | GO:0004170 | dUTP diphosphatase activity |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Biological Process | GO:0046081 | dUTP catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.