Search Results
Overview
| Uniprot ID | A0A4X1SPZ5 |
|---|---|
| Protein Name | GMP reductase |
| Gene Name | GMPR2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 237 | SSEMAMKKYAGGVAE |
| 258 | KTVEVPFKGAVEHTI |
Function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation
Protein Sequence
10
MPHIDNDVKL
20
DFKDVLLRPK
30
RSTLKSRSEF
40
SLFTAVHKHY
50
SLEQWKEFAS
60
QNPDCLEHLA
70
ASSGTGSSDF
80
EQLEQILDAI
90
PQVKYICLDV
100
ANGYSEHFVE
110
FVKDVRKRFP
120
EHTIMAGNVV
130
TGEMVEELIL
140
SGADIIKVGI
150
GPGSVCTTRK
160
KTGVGYPQLS
170
AVMECADAAH
180
GLKGHIISDG
190
GCSCPGDVAK
200
AFGAGADFVM
210
LGGMLAGHSE
220
SGGELIERNG
230
KKYKLFYGMS
240
SEMAMKKYAG
250
GVAEYRASEG
260
KTVEVPFKGA
270
VEHTIRDILG
280
GIRSTCTYVG
290
AAKLKELSRR
300
TTFIRVTQQV
NPIFSDES
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:1902560 | GMP reductase complex |
| Molecular Function | GO:0003920 | GMP reductase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0006144 | purine nucleobase metabolic process |
| Biological Process | GO:0006163 | purine nucleotide metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.