Search Results

Overview

Uniprot ID	A0A4X1SQF0
Protein Name	DnaJ homolog subfamily C member 10
Gene Name	DNAJC10
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
748	IRAYPTVKFYPYEGT

Function

Endoplasmic reticulum disulfide reductase that collaborates directly with a BIP/HSPA5 (GRP78)-type chaperone to maintain protein quality control by facilitating either the correct folding or the targeted degradation of misfolded proteins

Protein Sequence

10 MGVWLNKDAY 20 IRDLKRVILC 30 FLLVYMAILV 40 GTDQDFYSLL 50 GVSKTASSRE 60 IRQAFKKLAL 70 KLHPDKNPNN 80 PNAHSDFLKI 90 NKAYEVLKDE 100 DLRKKYDKYG 110 EKGLADNQGG 120 GQYESWNYYR 130 YDFGIYDDDP 140 EIITLDRSEF 150 DAAVNSGELW 160 FVNFYSSGCS 170 HCHDLAPTWR 180 DFAREVDGLL 190 RIGAVNCGDD 200 RMLCRMKGVS 210 SYPSLFIFRS 220 GMAAVKYHGD 230 RSKESLVNFA 240 MQYVRSTVTE 250 LWTGNFVNSI 260 QTAFAAGIGW 270 LITFCSKGGD 280 CLTSQTRLRL 290 SGMLDGLVNV 300 GWMDCATQDN 310 LCKSLDITTS 320 TTAYFPPGAT 330 LNNKEKSSIL 340 FLNSLDAKEI 350 YLEIMHNLPD 360 FELLSANTLE 370 DRLAHHRWLL 380 FFYFGKNEFS 390 NDPELKKLKT 400 LLKNEHIQVG 410 KFDCSSAPDI 420 CSNLYVFQPC 430 LAVFKGQGTK 440 EFEIHHGKKI 450 LYDILAFAKE 460 SVNSHVTTLG 470 PQNFPTSDKE 480 PWLVDFFAPW 490 CPPCRALLPE 500 LRKASKHLYG 510 QLKFGTLDCT 520 VHEGLCNMYN 530 IQAYPTTVVF 540 NQSNIHEYEG 550 HHSAEQILEF 560 VEDLMNPSVV 570 SLTPTTFDEL 580 VRQRKPDEVW 590 MVDFYSPWCH 600 PCQVLMPEWK 610 RMARTLTGLI 620 NVGSIDCQQY 630 HSLCAQENVR 640 RYPEIRFFPQ 650 KSNKAYQYHS 660 YNGWNRDAYS 670 LRIWGLGFLP 680 QASIDLTPQT 690 FNEKVLQGKS 700 HWVVDFYAPW 710 CGPCQNFAPE 720 FELLARMVKE 730 KVKAGKVDCQ 740 AYAQTCQKAG 750 IRAYPTVKFY 760 PYEGTRRNIW 770 GEQIDSRDAK 780 EITTLIYEKL 790 ENLQNHGKRN KDEL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005788	endoplasmic reticulum lumen
Molecular Function	GO:0051117	ATPase binding
Molecular Function	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Molecular Function	GO:0015035	protein-disulfide reductase activity
Molecular Function	GO:0051087	protein-folding chaperone binding
Biological Process	GO:0036503	ERAD pathway
Biological Process	GO:0034975	protein folding in endoplasmic reticulum

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.