Search Results
Overview
| Uniprot ID | A0A4X1SSR6 |
|---|---|
| Protein Name | Catalase |
| Gene Name | CAT |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 260 | VYCKFHYKTDQGIKN |
| 266 | YKTDQGIKNLSVEDA |
| 499 | DAQLFIQKKAVKNFS |
Function
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells
Protein Sequence
10
MSSFREMQLP
20
NGFFSELDTM
30
SDTMADNRDP
40
ASDQMKHWKE
50
QRAAQKPDIL
60
TTGSGNPIGD
70
KLNILTAGPR
80
GPLLVQDVVF
90
TDEMAHFDRE
100
RIPERVVHAK
110
GAGAFGYFEV
120
THDITRFSKA
130
KVFEHVGKRT
140
PIAVRFSTVA
150
GESGSADTVR
160
DPRGFAVKFY
170
TEDGNWDLVG
180
NNTPIFFIRD
190
AILFPSFIHS
200
QKRNPQTHLK
210
DPDMVWDFWS
220
LRPESLHQVS
230
FLFSDRGIPD
240
GHRHMNGYGS
250
HTFKLVNEKG
260
EAVYCKFHYK
270
TDQGIKNLSV
280
EDAARLSQED
290
PDYGIRDLFN
300
AIATGNYPSW
310
TFYIQVMTFQ
320
EAEAFPFNPF
330
DLTKVWPHSE
340
YPLIPVGKLV
350
LNRNPVNYFA
360
EVEQMAFDPS
370
NMPPGIEPSP
380
DKMLQGRLFA
390
YPDTHRHRLG
400
PNYLQIPVNC
410
PFRARVANYQ
420
RDGPMCFQDN
430
QGGAPNYYPN
440
SFSAPEQTHS
450
ALEHCTRYSG
460
DVQRFNSANE
470
DNVTQVRTFY
480
LNVLNEEERK
490
RLCENIAGHL
500
KDAQLFIQKK
510
AVKNFSDVHP
520
DYGARIQALL
530
DKYNAEKPKN
540
AVHTYVQAGS
550
HLAAREKANL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005782 | peroxisomal matrix |
| Cellular Component | GO:0005778 | peroxisomal membrane |
| Cellular Component | GO:0005777 | peroxisome |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0004046 | aminoacylase activity |
| Molecular Function | GO:0004096 | catalase activity |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0050661 | NADP binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0061692 | cellular detoxification of hydrogen peroxide |
| Biological Process | GO:0042744 | hydrogen peroxide catabolic process |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
| Biological Process | GO:0009650 | UV protection |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.