Search Results
Overview
| Uniprot ID | A0A4X1SWJ9 |
|---|---|
| Protein Name | 26S proteasome non-ATPase regulatory subunit 12 |
| Gene Name | PSMD12 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 127 | IERARLTKTLATIKE |
| 187 | IRTQIISKKINTKFF |
| 192 | ISKKINTKFFQEENT |
| 201 | FQEENTEKLKLKYYN |
| 385 | VNKTIFAKVDRLAGI |
| 78 | SKRRSQLKQAVAKMV |
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair
Protein Sequence
10
MADGGSERAD
20
GRIVKMEVDY
30
SATVDQRLPE
40
CEKLAKASDM
50
VSTSRILVAV
60
VKMCYEAKEW
70
DLLNENIMLL
80
SKRRSQLKQA
90
VAKMVQQCCT
100
YVEEITDLPV
110
KLRLIDTLRM
120
VTEGKIYVEI
130
ERARLTKTLA
140
TIKEQNGDVK
150
EAASILQELQ
160
VETYGSMEKK
170
ERVEFILEQM
180
RLCLAVKDYI
190
RTQIISKKIN
200
TKFFQEENTE
210
KLKLKYYNLM
220
IQLDQHEGSY
230
LSICKHYRAI
240
YDTPCIQAES
250
EKWQQALKSV
260
VLYVILAPFD
270
NEQSDLVHRI
280
SGDKKLEEIP
290
KYKDLLKLFT
300
TMELMRWSTL
310
VEDYGMELRK
320
GSLESPATDV
330
FGYTEEGEKR
340
WKDLKNRVVE
350
HNIRIMAKYY
360
TRITMKRMAQ
370
LLDLSVDESE
380
AFLSNLVVNK
390
TIFAKVDRLA
400
GIINFQRPKD
410
PNNLLNDWSQ
420
KLNSLMSLVN
430
KTTHLIAKEE
MIHNLQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000502 | proteasome complex |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.