Search Results
Overview
| Uniprot ID | A0A4X1SYV7 |
|---|---|
| Protein Name | Aspartate--tRNA ligase, cytoplasmic |
| Gene Name | DARS1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 41 | HTSRAKGKQCFLVLR |
| 418 | HHGIDLEKIKAYIDS |
| 420 | GIDLEKIKAYIDSFR |
| 93 | VVRKVNQKIGSCTQQ |
Function
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA
Protein Sequence
10
MIQSQEKPDR
20
VLVRVSDLTV
30
QKADEVVWVR
40
ARVHTSRAKG
50
KQCFLVLRQQ
60
QFNVQALVAV
70
GDHASKQMVK
80
FAANINKESI
90
VDVEGVVRKV
100
NQKIGSCTQQ
110
DVELHVQKIY
120
VISSAEPRLP
130
LQLDDAVRPE
140
VEGEEEGRAT
150
VNQDTRLDNR
160
IIDLRTSTSQ
170
AVFRLQSGIC
180
HLFRENLINK
190
GFVEIQTPKI
200
ISAASEGGAN
210
VFTVSYFKNN
220
AYLAQSPQLY
230
KQMCICADFE
240
KVFCIGPVFR
250
AEDSNTHRHL
260
TEFVGMDIEM
270
VFNYHYHEVV
280
EEIADTLVQI
290
FKGLQERFQT
300
EIQMVNKQFP
310
CEPFKFLEPT
320
LRLEYCEALA
330
MLREAGIEMG
340
DEEDLSTPNE
350
KLLGRLVKEK
360
YDTDFYILDK
370
YPLAVRPFYT
380
MPDPRNPKQS
390
NSYDMFMRGE
400
EILSGAQRIH
410
DPQLLTERAL
420
HHGIDLEKIK
430
AYIDSFRFGA
440
PPHAGGGIGL
450
ERVTMLFLGL
460
HNVRQTSMFP
RDPKRLTP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex |
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0004815 | aspartate-tRNA ligase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003676 | nucleic acid binding |
| Biological Process | GO:0006422 | aspartyl-tRNA aminoacylation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.