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Overview

Uniprot IDA0A4X1SZM8
Protein NameDynein light chain roadblock
Gene NameDYNLRB2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
9 AEVEETLKRIQSHKG

Function

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules

Protein Sequence

10 MAEVEETLKR 20 IQSHKGVIGT 30 MVVNAEGIPI 40 RTTLDNSTTV 50 QYAGLLHQLT 60 VKAKGTVRDI 70 DPQNDLTFLR 80 IRSKKHEIMV 90 APDKEYLLIV IQNPCE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005868 cytoplasmic dynein complex
Cellular Component GO:0005874 microtubule
Molecular Function GO:0045505 dynein intermediate chain binding
Biological Process GO:0007018 microtubule-based movement

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.