Search Results

Overview

Uniprot IDA0A4X1SZP7
Protein NameNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Gene NameNDUFV1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
137 IIRHDPHKLVEGCLV
365 DRSTDIVKAIARLIE

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I

Protein Sequence

10 MLAARRLLGG 20 SLPARVSVRF 30 SGDTTAPKKT 40 SFGSLKDEDR 50 IFTNLYGRHD 60 WRLKGAQSRG 70 DWYKTKEILL 80 KGPDWILGEV 90 KTSGLRGRGG 100 AGFPTGLKWS 110 FMNKPSDGRP 120 KYLVVNADEG 130 EPGTCKDREI 140 IRHDPHKLVE 150 GCLVGGRAMG 160 ARAAYIYIRG 170 EFYNEASNLQ 180 VAIREAYEAG 190 LIGKNACGSG 200 YDFDVFVVRG 210 AGAYICGEET 220 ALIESIEGKQ 230 GKPRLKPPFP 240 ADVGVFGCPT 250 TVANVETVAV 260 SPTICRRGGA 270 WFASFGRERN 280 SGTKLFNISG 290 HVNHPCTVEE 300 EMSVPLKELI 310 EKHAGGVIGG 320 WDNLLAVIPG 330 GSSTPLIPKS 340 VCETVLMDFD 350 ALVQAQTGLG 360 TAAVIVMDRS 370 TDIVKAIARL 380 IEFYKHESCG 390 QCTPCREGVD 400 WMNKVMARFV 410 KGDARPAEID 420 SLWEISKQIE 430 GHTICALGDG 440 AAWPVQGLIR 450 HFRPELEERM 460 QQFALQHQAR QAAS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0045271 respiratory chain complex I
Molecular Function GO:0051539 4 iron, 4 sulfur cluster binding
Molecular Function GO:0010181 FMN binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0051287 NAD binding
Molecular Function GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process GO:0006120 mitochondrial electron transport, NADH to ubiquinone

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.