Search Results
Overview
| Uniprot ID | A0A4X1T868 |
|---|---|
| Protein Name | Gamma-glutamylcyclotransferase |
| Gene Name | GGCT |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 118 | NVSAQKGKEITCRSY |
Function
Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis
Protein Sequence
10
MANSGGEDRG
20
GQEEESFLYF
30
AYGSNLLMER
40
IHLRNPSAEF
50
YCVARLQDFK
60
LDFGNSQGKT
70
SETWHGGIAT
80
IFESPGDEVW
90
GVVWKMNKSN
100
LSSLDEQEGV
110
KSGMYVPIEV
120
NVSAQKGKEI
130
TCRSYQMTNY
140
ESAPPSPQYK
150
KIICTGAKEN
160
GLPLEYQKKL
170
NAIEPNDYKG
180
KVSEEIEDII
KRGETKAH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0003839 | gamma-glutamylcyclotransferase activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0001836 | release of cytochrome c from mitochondria |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.