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Overview

Uniprot IDA0A4X1T8E4
Protein NamePrefoldin subunit 3
Gene NameVBP1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
148 RVYNWDVKRRNKDDS
38 AQKKRRLKGQIPEIK

Function

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins

Protein Sequence

10 MKQPGNETAD 20 TVLKKLDEQY 30 QKYKFMELNL 40 AQKKRRLKGQ 50 IPEIKQTLEI 60 LKYMQKKKES 70 TSSLETRFLL 80 ADNLYCKASV 90 PPTDKVCLWL 100 GANVMLEYDI 110 DEAQALLEKN 120 LSTATKNLDS 130 LEEDLDFLRD 140 QFTTTEVNMA 150 RVYNWDVKRR 160 NKDDSTKNKA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0016272 prefoldin complex
Biological Process GO:0006457 protein folding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.