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Overview

Uniprot IDA0A4X1T8K5
Protein NameNuclear transcription factor Y subunit beta
Gene NameNFYB
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
77 NAIPQTGKIAKDAKE

Function

Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors

Protein Sequence

10 MTMDGDSSTT 20 DASQLGISAD 30 YIGGSHYVIQ 40 PHDDTEDSMN 50 DHEDTNGSKE 60 SFREQDIYLP 70 IANVARIMKN 80 AIPQTGKIAK 90 DAKECVQECV 100 SEFISFITSE 110 ASERCHQEKR 120 KTINGEDILF 130 AMSTLGFDSY 140 VEPLKLYLQK 150 FREAMKGEKG 160 IGGAVTATDG 170 LSEELTEEAF 180 TNQLPAGLIT 190 ADGQQQNVMV 200 YTTSYQQISG VQQIQFS

Gene Ontology

Classification GO ID Description
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0140297 DNA-binding transcription factor binding
Molecular Function GO:0046982 protein heterodimerization activity
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component GO:0016602 CCAAT-binding factor complex
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0032993 protein-DNA complex
Molecular Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.