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Overview

Uniprot IDA0A4X1T9A9
Protein NamePrefoldin subunit 3
Gene NameVBP1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
180 RVYNWDVKRRNKDDS
70 AQKKRRLKGQIPEIK

Function

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins

Protein Sequence

10 MTPQPMFSTP 20 LGFSTGPPSA 30 PSTRHKEDVD 40 SFMKQPGNET 50 ADTVLKKLDE 60 QYQKYKFMEL 70 NLAQKKRRLK 80 GQIPEIKQTL 90 EILKYMQKKK 100 ESTSSLETRF 110 LLADNLYCKA 120 SVPPTDKVCL 130 WLGANVMLEY 140 DIDEAQALLE 150 KNLSTATKNL 160 DSLEEDLDFL 170 RDQFTTTEVN 180 MARVYNWDVK 190 RRNKDDSTKN KA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0016272 prefoldin complex
Biological Process GO:0006457 protein folding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.