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Overview

Uniprot IDA0A4X1TD48
Protein NamerRNA-processing protein FCF1 homolog
Gene NameFCF1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
137 ERLPCTHKGTYADDC

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MGKQKKTRKY 20 AIMKRMLSLR 30 DQRLKEKDRL 40 KPKKKEKKDP 50 SALKEREVPQ 60 HPSCLFFQYN 70 TQLGPPYHIL 80 VDTNFINFSI 90 KAKLDLVQSM 100 MDCLYAKCIP 110 CITDCVMAEI 120 EKLGQKYRVA 130 LRIAKDPRFE 140 RLPCTHKGTY 150 ADDCLVQRVT 160 QHKCYIVATV 170 DRDLKRRIRK 180 IPGVPIMYIS 190 NHRYNIERMP DDYGAPRF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0032040 small-subunit processome
Biological Process GO:0042274 ribosomal small subunit biogenesis
Biological Process GO:0006364 rRNA processing

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.