Search Results

Overview

Uniprot IDA0A4X1TDZ9
Protein NameUnconventional myosin-Id
Gene NameMYO1D
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
108 SGESGAGKTEASKYI
152 LEAFGNAKTNRNDNS
188 INNYLLEKSRVIVQQ
329 TGRDVIDKQHTEQEA
345 YGRDAFAKAIYERLF
366 INDIIEVKRSDATIH
489 HGHFSSRKLCASDKI
495 RKLCASDKILEFDRD
524 VGFIDKNKDTLFQDF
532 DTLFQDFKRLMYNSS
559 LSITEVTKRPLTAAT
596 CIKPNDKKSPQIFDD
634 AYRQTYEKFLHRYKM
67 RDTIEQYKGRELYER
676 QDDVAYGKTKIFIRT
737 YYRRYKVKSYIHEVA
871 RKVNRFSKVEDRAIF
94 KAMKRRSKDTCIVIS
975 VQCSLHGKKCTVSVE
976 QCSLHGKKCTVSVET

Function

Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells

Protein Sequence

10 MAEQESLEFG 20 KADFVLMDTV 30 SMPEFMANLR 40 LRFEKGRIYT 50 FIGEVVVSVN 60 PYRLLNIYGR 70 DTIEQYKGRE 80 LYERPPHLFA 90 IADAAYKAMK 100 RRSKDTCIVI 110 SGESGAGKTE 120 ASKYIMQYIA 130 AITNPSQRAE 140 IERVKNMLLK 150 SNCVLEAFGN 160 AKTNRNDNSS 170 RFGKYMDINF 180 DFKGDPIGGH 190 INNYLLEKSR 200 VIVQQPGERS 210 FHSFYQLLQG 220 GSEQMLHSLH 230 LQKSLSSYNY 240 IHVGAQLKSS 250 INDAAEFKVV 260 ADAMKVIGFK 270 PEEIQTVYKI 280 LAAILHLGNL 290 KFVVDGDTPL 300 IENGKVVSII 310 ADLLSTKPDM 320 VEKALLYRTV 330 ATGRDVIDKQ 340 HTEQEASYGR 350 DAFAKAIYER 360 LFCWIVSRIN 370 DIIEVKRSDA 380 TIHGKNTVIG 390 VLDIYGFEIF 400 DNNSFEQFCI 410 NYCNEKLQQL 420 FIQLVLKQEQ 430 EEYQREGIPW 440 KHIDYFNNQI 450 IVDLVEQQHK 460 GIIAILDDAC 470 MNVGKVTDEM 480 FLGALNSKLG 490 KHGHFSSRKL 500 CASDKILEFD 510 RDFRIRHYAG 520 DVVYSVVGFI 530 DKNKDTLFQD 540 FKRLMYNSSN 550 PVLKNMWPEG 560 KLSITEVTKR 570 PLTAATLFKN 580 SMIALVDNLA 590 SKEPYYVRCI 600 KPNDKKSPQI 610 FDDDRCRHQV 620 EYLGLLENVR 630 VRRAGFAYRQ 640 TYEKFLHRYK 650 MISEFTWPNH 660 DLPSDKEAVK 670 KLIEHCGFQD 680 DVAYGKTKIF 690 IRTPRTLFTL 700 EELRAQMLVR 710 IVLFLQKVWR 720 GTLARMRYKR 730 TKAALTIIRY 740 YRRYKVKSYI 750 HEVARRFHGI 760 RTMRDYGKHV 770 QWPTPPKVLC 780 RFEEALQAIF 790 NRWRASQLIK 800 TIPASDLPQV 810 RAKVAAVEML 820 KGQRADLGLQ 830 RAWEGNYLAS 840 KPDTPQTSGT 850 FVPVANELKR 860 KDKYMNVLFS 870 CHVRKVNRFS 880 KVEDRAIFVT 890 DRHLYKMDPT 900 KQYKVMKTIP 910 LYNLTGLSVS 920 NGKDQLVVFH 930 TKDNKDLIVC 940 LFSKQPTHES 950 RIGELVGVLV 960 NHFKSEKRHL 970 QVNVTNPVQC 980 SLHGKKCTVS 990 VETRLNQPQP 1000 DFTKNRSGFI LSVPGN

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0030424 axon
Cellular Component GO:0005903 brush border
Cellular Component GO:0005938 cell cortex
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0030425 dendrite
Cellular Component GO:0005769 early endosome
Cellular Component GO:0005902 microvillus
Cellular Component GO:0043209 myelin sheath
Cellular Component GO:0016459 myosin complex
Cellular Component GO:0043204 perikaryon
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0005516 calmodulin binding
Molecular Function GO:0000146 microfilament motor activity
Molecular Function GO:0019904 protein domain specific binding
Biological Process GO:0007015 actin filament organization
Biological Process GO:0030048 actin filament-based movement
Biological Process GO:0006897 endocytosis
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.