Search Results
Overview
| Uniprot ID | A0A4X1TQF8 |
|---|---|
| Protein Name | DCN1-like protein |
| Gene Name | DCUN1D5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 23 | VAEDGSLKKCKISRC |
| 8 | MPVKKKRKSSGVAAA |
Function
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth
Protein Sequence
10
MPVKKKRKSS
20
GVAAAVAEDG
30
SLKKCKISRC
40
DCTEKLQNKF
50
DFLRSQLNDI
60
SSFKNIYRYA
70
FDFARDKDQR
80
SLDIDTAKSM
90
LALLLGRTWP
100
LFSVFYQYLE
110
QSKYRVMNKD
120
QWYNVLEFSR
130
TVHADLSNYD
140
EDGAWPVLLD
150
EFVEWQKVRQ
TS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005819 | spindle |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.