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Overview

Uniprot IDA0A4X1TTH9
Protein NamePhosphatidylethanolamine-binding protein 1
Gene NamePEBP1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
150 GDHRGKFKVASFRKK
47 VLTPTQVKSRPTSIT

Function

HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor

Protein Sequence

10 MPVDLGKWSG 20 PLSLQEVDER 30 PQHPLQVKYG 40 GAEVDELGKV 50 LTPTQVKSRP 60 TSITWDGLNP 70 DKLYTLVLTD 80 PDAPSRKDPK 90 YREWHHFLVV 100 NMKGNDISSG 110 TVLSDYVGSG 120 PPKGTGLHRY 130 VWLVYEQDGP 140 LKCDEPILSN 150 RSGDHRGKFK 160 VASFRKKYQL 170 GAPVAGTCYQ 180 AEWDDYVPKL YEQLSGK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0009986 cell surface
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0008289 lipid binding
Molecular Function GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process GO:0043409 negative regulation of MAPK cascade

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.