Search Results
Overview
| Uniprot ID | A0A4X1U6S6 |
|---|---|
| Protein Name | Large ribosomal subunit protein bL12m |
| Gene Name | MRPL12 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 163 | INLVQAKKLVESLPQ |
Function
As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability
Protein Sequence
10
MLPAAASSLW
20
GPCFGLRAAA
30
LRVARHQGPR
40
LCGVRLMRCS
50
SHRKGEALAG
60
APLDNAPKEY
70
PPKIQQLVQD
80
IASLTLLEIS
90
DLNELLKKTL
100
KIQDVGFMPM
110
GAVAPGAPPA
120
AAAPEAAEED
130
LPKRKEQTHF
140
TVRLTEAKPV
150
DKVKLIKEIK
160
SHIQGINLVQ
170
AKKLVESLPQ
180
EIKANVPKAE
190
AEKIKAALEA
VGGTVVLE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005762 | mitochondrial large ribosomal subunit |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:0006390 | mitochondrial transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0006412 | translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.