Search Results
Overview
| Uniprot ID | A0A4X1UNX9 |
|---|---|
| Protein Name | Transcriptional enhancer factor TEF-3 |
| Gene Name | TEAD4 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 91 | YPPCGRRKIILSDEG |
Function
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
Protein Sequence
10
MEILAGTAVC
20
LKLAQYCPTG
30
APPSGALEGK
40
AGTITSNEWS
50
SPNSPEGSNV
60
SGGSQALDKP
70
IDNDAEGVWS
80
PDIEQSFQEA
90
LAIYPPCGRR
100
KIILSDEGKM
110
YGRNELIARY
120
IKLRTGKTRT
130
RKQVSSHIQV
140
LARRKAREIQ
150
AKLKDQAAKD
160
KALQSMATMS
170
SAQIISASAF
180
HNKMALARGP
190
GYPAVSGFWQ
200
GALPGQAGTS
210
HDVKPFSQQT
220
YTVQPSLPLP
230
GFESPSGHTP
240
SPSAPPAPPW
250
QGRSVASSKL
260
WMLEFSAFLE
270
RQQDPDTYNK
280
HLFVHIGQSS
290
PSYSDPYLEA
300
VDIRQIYDKF
310
PEKKGGLKEL
320
FERGPSNAFF
330
LVKFWADLNT
340
NIEDEGSSFY
350
GVSSQYESPE
360
NMIITCSTKV
370
CSFGKQVVEK
380
VETEYARYEN
390
GHYSYRIHRS
400
PLCEYMVNFI
410
HKLKHLPEKY
420
MMNSVLENFT
430
ILQVVTNRDT
440
QETLLCVAYV
450
FEVSASEHGA
460
QHHIYRLVKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0032993 | protein-DNA complex |
| Cellular Component | GO:0005667 | transcription regulator complex |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0048568 | embryonic organ development |
| Biological Process | GO:0035329 | hippo signaling |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.