Search Results
Overview
| Uniprot ID | A0A4X1UT36 |
|---|---|
| Protein Name | 26S proteasome non-ATPase regulatory subunit 5 |
| Gene Name | PSMD5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | THTNDSVKILTLSQV |
| 334 | EGKQVLQKTGTRFER |
| 358 | KNASTELKIRCLDAV |
| 85 | VHVARNLKVDLQRGL |
Function
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5
Protein Sequence
10
MAAQVLALLR
20
EVSRLEAPLE
30
ELRALQSVLQ
40
SVPLSELREH
50
AAELHLGPLF
60
SLLNENHREQ
70
TTLCVSILER
80
LLQALEPVHV
90
ARNLKVDLQR
100
GLTHTNDSVK
110
ILTLSQVGRI
120
VDNSDAVTEI
130
LNNAELLKQI
140
VYCIGGENLS
150
VAKAAIKSLS
160
RISLTQAGLE
170
ALFESNLLDD
180
LKSVMKTNDI
190
VRYRVYELIV
200
EISSVSPESL
210
NYCTTSGLVT
220
QLLRELTGED
230
VLVRATCIEM
240
VTSLAYTHHG
250
RQYLAQEGVI
260
DQISNIIVGA
270
DSDPFSSFYL
280
PGFVKFFGNL
290
AIMDSPQQIC
300
ERYPVFVEKV
310
FEMTESQDPT
320
MIGVAVDTIG
330
ILGSNVEGKQ
340
VLQKTGTRFE
350
RLLMKIGYQA
360
KNASTELKIR
370
CLDAVSSLFY
380
LPPEQQTDDL
390
LRMTESWFSS
400
LSRDPLELFR
410
GISNQPFPEL
420
HCAALKVFTA
430
IANQPWAQKL
440
MFNSPGFVEY
450
VMDRSVEHDK
460
ASKDAKYELV
470
KALANSKTIA
480
EIFGNPNYLR
490
LRTYLSEGPY
500
YVKPISTTAV
EGAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0008540 | proteasome regulatory particle, base subcomplex |
| Biological Process | GO:0070682 | proteasome regulatory particle assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.