Search Results
Overview
| Uniprot ID | A0A4X1UWK0 |
|---|---|
| Protein Name | Purine nucleoside phosphorylase |
| Gene Name | PNP |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 253 | ILDYECQKKANHEEV |
| 254 | LDYECQKKANHEEVL |
| 265 | EEVLEAGKQAAQKLE |
Function
Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine
Protein Sequence
10
MENGFTFEDY
20
QNTAKWLLSH
30
TKHRPQVAVI
40
CGSGLGGLTD
50
RLTETQIFNY
60
SEIPNFPRST
70
VPGHAGRLVF
80
GILNGRACVM
90
MQGRFHLYEG
100
YPLWKVTFPV
110
RVFQLLGVDT
120
LVVTNAAGGL
130
NPRFEVGDIM
140
LIRDHINLPG
150
FCGENPLRGP
160
NDERFGVRFP
170
AMSDAYDRDM
180
RQKAHSTWKE
190
MGEQRELQEG
200
TYVMVAGPSF
210
ETVAECRLLQ
220
KLGADAVGMS
230
TVPEVIVARH
240
CGLRVFGFSL
250
ITNKVILDYE
260
CQKKANHEEV
270
LEAGKQAAQK
280
LEQFVSILIA
GIPPPKAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0004731 | purine-nucleoside phosphorylase activity |
| Biological Process | GO:0006166 | purine ribonucleoside salvage |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.