Search Results
Overview
| Uniprot ID | A0A4X1UYU9 |
|---|---|
| Protein Name | Core histone macro-H2A |
| Gene Name | MACROH2A1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 134 | IITPPPAKKAKSPSQ |
| 18 | TKTSRSAKAGVIFPV |
| 284 | SPVWGADKCEELLEK |
| 294 | ELLEKTVKNCLALAD |
| 303 | CLALADDKKLKSIAF |
| 306 | LADDKKLKSIAFPSI |
Function
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes
Protein Sequence
10
MSSRGGKKKS
20
TKTSRSAKAG
30
VIFPVGRMLR
40
YIKKGHPKYR
50
IGVGAPVYMA
60
AVLEYLTAEI
70
LELAGNAARD
80
NKKGRVTPRH
90
ILLAVANDEE
100
LNQLLKGVTI
110
ASGGVLPNIH
120
PELLAKKRGS
130
KGKLEAIITP
140
PPAKKAKSPS
150
QKKPVSKKTG
160
GKKGARKSKK
170
QGEVSKAASA
180
DSTTEGTPAD
190
GFTVLSTKSL
200
FLGQKLNLIH
210
SEISNLAGFE
220
VEAIINPTNA
230
DIDLKDDLGN
240
TLEKKGGKEF
250
VEAVLELRKK
260
NGPLEVAGAA
270
VSAGHGLPAK
280
FVIHCNSPVW
290
GADKCEELLE
300
KTVKNCLALA
310
DDKKLKSIAF
320
PSIGSGRNGF
330
PKQTAAQLIL
340
RAISSYFVST
350
MSSSIKTVYF
360
VLFDSESIGI
370
YVQEMAKLDA
N
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0031490 | chromatin DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0006334 | nucleosome assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.