Search Results
Overview
| Uniprot ID | A0A4X1UZN2 |
|---|---|
| Protein Name | V-type proton ATPase subunit G |
| Gene Name | ATP6V1G1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 21 | AEKRAAEKVSEARKR |
| 58 | REKEFKAKEAAALGS |
| 75 | SCSTEVEKDTQEKMT |
Function
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment
Protein Sequence
10
MASQSQGIQQ
20
LLQAEKRAAE
30
KVSEARKRKN
40
RRLKQAKEEA
50
QAEIEQYRLQ
60
REKEFKAKEA
70
AALGSHGSCS
80
TEVEKDTQEK
90
MTILQTYFRQ
100
NRDEVLDNLL
110
AFVCDIRPEI
HENYRING
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005765 | lysosomal membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Cellular Component | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain |
| Molecular Function | GO:0051117 | ATPase binding |
| Molecular Function | GO:0046961 | proton-transporting ATPase activity, rotational mechanism |
| Biological Process | GO:0036295 | cellular response to increased oxygen levels |
| Biological Process | GO:0006879 | intracellular iron ion homeostasis |
| Biological Process | GO:0097401 | synaptic vesicle lumen acidification |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.