Search Results

Overview

Uniprot IDA0A4X1VMS1
Protein NameSyntaxin-5
Gene NameSTX5
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
114 NTFAKLEKLTILAKR
122 LTILAKRKSLFDDKA

Function

Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus

Protein Sequence

10 MIPRKRYGSK 20 NTDQGVYLGL 30 SKTQVLSPAT 40 AGSSSSDIAP 50 LPPPVALAPP 60 PPDTMSCRDR 70 TQEFLSACKS 80 LQSRQNGIQT 90 NKPALRAVRQ 100 RSEFTLMAKR 110 IGKDLSNTFA 120 KLEKLTILAK 130 RKSLFDDKAV 140 EIEELTYIIK 150 QDINSLNKQI 160 AQLQDFVRAK 170 GSQSGRHLQT 180 HSNTIVVSLQ 190 SKLASMSNDF 200 KSVLEVRTEN 210 LKQQRSRREQ 220 FSRAPVSALP 230 LAPNHLGGGA 240 VVLGAESRAS 250 GDVAIDMMDS 260 RTSQQLQLID 270 EQDSYIQTRA 280 DTMQNIESTI 290 VELGSIFQQL 300 AHMVKEQEET 310 IQRIDENVLG 320 AQLDVEAAHS 330 EILKYFQSVT 340 SNRWLMVKIF 350 LILIVFFIIF VVFLA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0012505 endomembrane system
Cellular Component GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Cellular Component GO:0000139 Golgi membrane
Cellular Component GO:0031201 SNARE complex
Cellular Component GO:0031982 vesicle
Molecular Function GO:0005484 SNAP receptor activity
Molecular Function GO:0000149 SNARE binding
Biological Process GO:0034498 early endosome to Golgi transport
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0090166 Golgi disassembly
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0045732 positive regulation of protein catabolic process
Biological Process GO:1903358 regulation of Golgi organization
Biological Process GO:0048278 vesicle docking
Biological Process GO:0006906 vesicle fusion

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.