Search Results
Overview
| Uniprot ID | A0A4X1VQG5 |
|---|---|
| Protein Name | Mitochondrial import inner membrane translocase subunit |
| Gene Name | TIMM10 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 45 | YKEAELSKGESVCLD |
| 57 | CLDRCVSKYLDIHER |
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space
Protein Sequence
10
MDPLRAQQLA
20
AELEVEMMAD
30
MYNRMTSACH
40
RKCVPPHYKE
50
AELSKGESVC
60
LDRCVSKYLD
70
IHERMGKKLT
80
ELSMQDEELM
90
KRVQQSSGPA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0042719 | mitochondrial intermembrane space chaperone complex |
| Cellular Component | GO:0042721 | TIM22 mitochondrial import inner membrane insertion complex |
| Molecular Function | GO:0032977 | membrane insertase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Biological Process | GO:0045039 | protein insertion into mitochondrial inner membrane |
| Biological Process | GO:0015031 | protein transport |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.