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Overview

Uniprot IDA0A4X1VWR3
Protein NameMitochondrial pyruvate carrier
Gene NameMPC1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
86 TFMRFAYKVQPRNWL

Function

Mediates the uptake of pyruvate into mitochondria

Protein Sequence

10 MCEAEITSSS 20 QSFQITDLSL 30 LSPQRLSCLN 40 LGDSSQNSTH 50 FWGPVANWGL 60 PIAAINDMKK 70 SPEIISGRMT 80 FALCCYSLTF 90 MRFAYKVQPR 100 NWLLFACHAT 110 NEVAQLIQGG 120 RLIRHEMSKK ASA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Biological Process GO:0006850 pyruvate import into mitochondria

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.