Search Results
Overview
| Uniprot ID | A0A4X1VY03 |
|---|---|
| Protein Name | Polymerase delta-interacting protein 3 |
| Gene Name | POLDIP3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 147 | TPALKLTKTIQVPQQ |
| 322 | VAEVVFVKKDDAITA |
Function
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex
Protein Sequence
10
MADISLDELI
20
RKRGAAAKGR
30
LNARPGVGGI
40
RSRVGIQQSL
50
LSQPARTATF
60
QQRFDARQKI
70
GLSDARLKLG
80
VKDAREKLLQ
90
KDARFRIKGK
100
VQDAREMLNS
110
RKQQSTVPQK
120
PRQVADAREK
130
ISLKRNSPAA
140
FMSPPIGTVT
150
PALKLTKTIQ
160
VPQQKAMAPV
170
HAHPAGMRIN
180
VVNNHQAKQN
190
LYDLDEDDDV
200
APIPSKQMKF
210
VAPGNFLHHV
220
AGLSSSKLSM
230
SKALPLTKVV
240
QNDAYTAPAL
250
PSSVRTKALT
260
NMSRTLVNKE
270
EPPKELPPAE
280
PVLSPLEGTK
290
MTVNNLHPRV
300
TEEDIVELFC
310
VCGALKRARL
320
VHPGVAEVVF
330
VKKDDAITAY
340
KKYNNRCLDG
350
QPMKCNLHMN
360
GNVITSDQPI
370
LLRLSDSPSV
380
KKESELPRRV
390
NSAGSSNPPA
400
EVDPDTILKA
410
LFKSSGASVT
420
TQPTEFKIKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0036464 | cytoplasmic ribonucleoprotein granule |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0016973 | poly(A)+ mRNA export from nucleus |
| Biological Process | GO:0045727 | positive regulation of translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.