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Overview

Uniprot ID	A0A4X1W634
Protein Name	MICOS complex subunit MIC60
Gene Name	IMMT
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
110	SEVMKESKQPASQLQ
329	QAAQSEAKVVSQYHE
399	NRALAEQKATEKQHI
541	VAEEEARKAHQLWLS
616	VRFYAVQKLARRVAM
690	AKFVNQLKGESRRVA
702	RVAQDWLKEARMTLE
90	YTVPLPKKSIQSGPL

Function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane

Protein Sequence

10 LLRLCLCGKF 20 VLRPLRPCRR 30 YSTSGSSRLS 40 PGKIAGAGIL 50 FVGGGIGGTI 60 LYAKWDSHFR 70 TNVEKTIPYS 80 DKLFEMVLGS 90 PPYTVPLPKK 100 SIQSGPLKIS 110 SVSEVMKESK 120 QPASQLQKQK 130 GDTSASITGD 140 TLSVPAPVVQ 150 HEESIKADRP 160 ATGEGKPKPA 170 TSEEASSTSV 180 RERPPEEVAA 190 RLAQQEKQEQ 200 VKIESLVKSL 210 EDALSQSAYI 220 TQQAIVAQNA 230 AVQAVTAHAN 240 ILKTAMDDSE 250 VAGEKKSAQW 260 RTVEGALKER 270 RKAVDEAADA 280 LLKAKEELEK 290 LKSVIENAKK 300 EEVAGAKSHI 310 TAAEGKLHSM 320 IVDLDNVVQK 330 VQAAQSEAKV 340 VSQYHELVVQ 350 ARDDFKRELD 360 SITPEVSPGW 370 KGMSISDLAD 380 RLSADDLNSL 390 IAHAHRRIDQ 400 LNRALAEQKA 410 TEKQHIALAL 420 EKQKLEEKRA 430 FDSAVAKALE 440 HHRSEIQAEQ 450 DRKVEEVRDA 460 MENEMRTQLR 470 RQAAAHTDHL 480 RDVLRVQEQE 490 LKYEFEQDLS 500 EKLTEQELQF 510 RRLSQEQVDN 520 FTLDINTAYA 530 RLRGIEQAVQ 540 SHAVAEEEAR 550 KAHQLWLSVE 560 ALKYSMKTAS 570 PDLPTVPLGS 580 AVEAVRASCS 590 DSEFTQALTA 600 ALPPESLTRG 610 VYSEETLRVR 620 FYAVQKLARR 630 VAMIDETRNS 640 LYQYFLSYLQ 650 SLLLFPPQQL 660 KPPAELCPED 670 TSTFKLLAYA 680 SYCIEHGDLE 690 LAAKFVNQLK 700 GESRRVAQDW 710 LKEARMTLET 720 KQIVEILTAY 730 ASAVGIGTTQ VQQE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.