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Overview

Uniprot IDA0A4X1W814
Protein NameGTP:AMP phosphotransferase AK3, mitochondrial
Gene NameAK3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
171 DKPETVVKRLKAYEA

Function

Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities

Protein Sequence

10 MGASARLLRA 20 AIMGAPGSGK 30 GTVSSRITKH 40 FELKHLSSGD 50 LLRDNMLRGT 60 EIGVLAKTFI 70 DQGKLIPDDV 80 MTRLVLHELK 90 NLTQYSWLLD 100 GFPRTLLQAE 110 ALDRVYQLDT 120 VINLNVPFEV 130 IKQRLTARWI 140 HPGSGRVYNI 150 EFNPPKTVGI 160 DDITGEPLVQ 170 REDDKPETVV 180 KRLKAYEAQT 190 EPVLEYYRKK 200 GVLETFSGTE 210 TNKIWPHVYA 220 FLQTKVPQIN QKTSVPP

Gene Ontology

Classification GO ID Description
Molecular Function GO:0005525 GTP binding
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005759 mitochondrial matrix
Molecular Function GO:0004017 AMP kinase activity
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0046899 nucleoside triphosphate adenylate kinase activity
Biological Process GO:0006172 ADP biosynthetic process
Biological Process GO:0046033 AMP metabolic process
Biological Process GO:0046039 GTP metabolic process
Biological Process GO:0046041 ITP metabolic process
Biological Process GO:0009142 nucleoside triphosphate biosynthetic process
Biological Process GO:0046051 UTP metabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.