Search Results
Overview
| Uniprot ID | A0A4X1WBM0 |
|---|---|
| Protein Name | Keratin, type II cytoskeletal 8 |
| Gene Name | KRT8 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 11 | RVTQKSYKVSTSGPR |
| 116 | KFASFIDKVRAPPAY |
Function
Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle
Protein Sequence
10
MSIRVTQKSY
20
KVSTSGPRSF
30
SSRSYTSGPG
40
TRISSSAFSR
50
VGSSSSSFRG
60
GLGSGMSLVG
70
GYGGPSGLGG
80
ITAVTVNQSL
90
LSPLKLEVDP
100
NIQAVRTQEK
110
EQIKTLNNKF
120
ASFIDKVRAP
130
PAYEEEIQKR
140
TDMENEFVII
150
KKDVDEAYMN
160
KVELESRLEG
170
LTDEINFYRQ
180
LYEEEIREMQ
190
SQISDTSVVL
200
SMDNSRSLDL
210
DGIIAEVKAQ
220
YEEIANRSRA
230
EAETMYQIKY
240
EELQSLAGKH
250
GDDLRRTKTE
260
ISEMNRNISR
270
LQAEIEGLKG
280
QRASLEAAIA
290
DAEQRGELAV
300
KDAQAKLAEL
310
EAALRTAKQD
320
MARQLREYQE
330
LMNVKLALDV
340
EIATYRKLLE
350
GEESRWVCVW
360
GSFAHPSGVT
370
YGTPGFNYSL
380
SSYQSGGLGS
390
VGGSGSFSRT
400
SSKAVVVKKI
410
ETRDGKLVSE
SSDVLSK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005882 | intermediate filament |
| Cellular Component | GO:0016363 | nuclear matrix |
| Cellular Component | GO:0005654 | nucleoplasm |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.