Search Results

Overview

Uniprot IDA0A5G2Q7J7
Protein NameTranscriptional enhancer factor TEF-5
Gene NameTEAD3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
57 YPPCGRRKIILSDEG

Function

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis

Protein Sequence

10 IASNSWNASS 20 SPGEAREDGP 30 EGLDKGLDND 40 AEGVWSPDIE 50 QSFQEALAIY 60 PPCGRRKIIL 70 SDEGKMYGRN 80 ELIARYIKLR 90 TGKTRTRKQV 100 SSHIQVLARK 110 KVREYQVGIK 120 AMNLDQVSKD 130 KALQSMASMS 140 SAQIVSASVL 150 QNKFSPPSPL 160 PQAVFSTSSR 170 FWSSPPLLGQ 180 QPGPSQDIKP 190 FAQPAYPVQP 200 PLPPTLSSYE 210 PLAPLPSAAA 220 SAPVWQDRTI 230 ASSRLRLLEY 240 SAFMEVQRDP 250 DTYSKHLFVH 260 IGQNPAFSDP 270 PLEAVDVRQI 280 YDKFPEKKGG 290 LKELYEKGPP 300 NAFFLVKFWA 310 DLNSTIQEGP 320 GAFYGVSSQY 330 SSAESMTISV 340 STKVCSFGKQ 350 VVEKVETEYA 360 RLENGRFVYR 370 IHRSPMCEYM 380 INFIHKLKHL 390 PEKYMMNSVL 400 ENFTILQVVT 410 SRDSQETLLV 420 IAFVFEVSTS 430 EHGAQHHVYK LVKD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005667 transcription regulator complex
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
Biological Process GO:0055059 asymmetric neuroblast division
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0048568 embryonic organ development
Biological Process GO:0035329 hippo signaling
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006357 regulation of transcription by RNA polymerase II

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.