Search Results
Overview
| Uniprot ID | A0A5G2Q8A9 |
|---|---|
| Protein Name | Septin |
| Gene Name | SEPTIN7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 166 | FMKRLHEKVNIIPLI |
| 188 | PEECQQFKKQIMKEI |
| 193 | QFKKQIMKEIQEHKI |
| 199 | MKEIQEHKIKIYEFP |
| 353 | KEKVQKLKDSEAELQ |
| 69 | GPSHRIKKTVQVEQS |
| 77 | TVQVEQSKVLIKEGG |
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Protein Sequence
10
IKQQKNLEGY
20
VGFANLPNQV
30
YRKSVKRGFE
40
FTLMVVGESG
50
LGKSTLINSL
60
FLTDLYSPEY
70
PGPSHRIKKT
80
VQVEQSKVLI
90
KEGGVQLLLT
100
IVDTPGFGDA
110
VDNSNCWQPV
120
IDYIDSKFED
130
YLNAESRVNR
140
RQMPDNRVQC
150
CLYFIAPSGH
160
GLKPLDIEFM
170
KRLHEKVNII
180
PLIAKADTLT
190
PEECQQFKKQ
200
IMKEIQEHKI
210
KIYEFPETDD
220
EEENKLVKKI
230
KDRLPLAVVG
240
SNTIIEVNGK
250
RVRGRQYPWG
260
VAEVENGEHC
270
DFTILRNMLI
280
RTHMQDLKDV
290
TNNVHYENYR
300
SRKLAAVTYN
310
GVDNNKNKGQ
320
LTKSPLAQME
330
EERREHVAKM
340
KKMEMEMEQV
350
FEMKVKEKVQ
360
KLKDSEAELQ
370
RRHEQMKKNL
380
EAQHKELEEK
390
RRQFEDEKAN
400
WEAQQRILEQ
410
QNSSRTLEKN
KKKGKIF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.