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Overview

Uniprot IDA0A5G2QA66
Protein Name-
Gene NameRFC2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
105 RLLNVIEKEKVPYTD
29 QQKVTLPKGRHKIII
89 CAVLRYTKLTDAQIL

Function

Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. This subunit binds ATP

Protein Sequence

10 TCPTSSLLGI 20 DVVRNKIKMF 30 AQQKVTLPKG 40 RHKIIILDEA 50 DSMTDGAQQA 60 LRRTMEIYSK 70 TTRFALACNA 80 SDKIIEPIQS 90 RCAVLRYTKL 100 TDAQILARLL 110 NVIEKEKVPY 120 TDDGLEAIIF 130 TAQGDMRQAL 140 NNLQSTFSGF 150 GFINSENVFK 160 VCDEPHPLLV 170 KEMIQHCVSA 180 NIDEAYKILA 190 HLWHLGYSPE 200 DIIGNIFRVC 210 KTFQMAEYLK 220 LEFIKEIGYT 230 HMRVAEGVNS 240 LLQMAGLLAR 250 LCQKTVAPVA S

Gene Ontology

Classification GO ID Description
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0003677 DNA binding
Biological Process GO:0006260 DNA replication

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.