Search Results
Overview
| Uniprot ID | A0A5G2QAL2 |
|---|---|
| Protein Name | Calponin |
| Gene Name | CNN3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 146 | IGVKYAEKQTRRFDE |
| 155 | TRRFDEGKLKAGQSV |
| 157 | RFDEGKLKAGQSVIG |
| 17 | YGLSAEVKNKIASKY |
| 23 | VKNKIASKYDHQAEE |
| 255 | TNKVASQKGMSVYGL |
| 6 | **MTHFNKGPSYGLS |
| 70 | KLQPGSVKKVNESSL |
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Protein Sequence
10
MTHFNKGPSY
20
GLSAEVKNKI
30
ASKYDHQAEE
40
DLRNWIEVTG
50
MSIGTSFQLG
60
LKDGIILCEL
70
INKLQPGSVK
80
KVNESSLNWP
90
QLENIGNFIK
100
AIQAYGMKPH
110
DIFEANDLFE
120
NGNMTQVQTT
130
LVALAGLAKT
140
KGFHTTIDIG
150
VKYAEKQTRR
160
FDEGKLKAGQ
170
SVIGLQMGTN
180
KCASQAGMTA
190
YGTRRHLYDP
200
KMQTDKPFDQ
210
TTISLQMGTN
220
KGASQAGMLA
230
PGTRRDIYDQ
240
KLTLQPVDNS
250
TISLQMGTNK
260
VASQKGMSVY
270
GLGRQVYDPK
280
YCAAPTEPVI
290
HNGSQGTGTN
300
GSEISDSDYQ
310
AEYPDEYHGE
320
YPDDYPRDYQ
YGDQGIDY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0031032 | actomyosin structure organization |
| Biological Process | GO:0030855 | epithelial cell differentiation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.