Search Results
Overview
| Uniprot ID | A0A5G2QBP1 |
|---|---|
| Protein Name | Receptor protein-tyrosine kinase |
| Gene Name | EGFR |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 269 | ENCQKLTKVICAQQC |
Function
No function data available.
Protein Sequence
10
MRRSWAGGAA
20
LLALLAAHFQ
30
ASPALEEKKG
40
WIFGFFLEKV
50
ASLFVHFYAL
60
RRPRAGTGHG
70
AQSLVQGILL
80
PETQPKARLD
90
RSWSRKVCQG
100
TSNKLTQLGT
110
FEDHFLSLQR
120
MFNNCEVVLG
130
NLEITYMQNS
140
YNLSFLKTIQ
150
EVAGYVLIAL
160
NTVEKIPLEN
170
LQIIRGNVLY
180
ENTHALAVLS
190
NYGANKTGLR
200
ELPMRNLQEI
210
LQGAVRFSNN
220
PALCHAESIQ
230
WRDIVNSDFL
240
SNMSMDFQSQ
250
LGSCPKCDPG
260
CLNGSCWGAG
270
KENCQKLTKV
280
ICAQQCSGRC
290
RGRSPSDCCH
300
NQCAAGCTGP
310
RESDCLVCRR
320
FRDEATCKDT
330
CPPLMLYNPT
340
TYQMDVNPLG
350
KYSFGATCVK
360
KCPRNYVVTD
370
HGSCVRACSS
380
DSYEVEEDGV
390
RKCKKCDGPC
400
GKVCNGIGIG
410
EFKDTLSINA
420
TNIKHFRNCT
430
SISGDLHILP
440
VAFRGDSFTR
450
TPPLDPKELD
460
ILKTVKEITG
470
FLLIQAWPEN
480
RTGLHAFENL
490
EIIRGRTKQH
500
GQFSLAVVGL
510
DIASLGLRSL
520
KEISDGDVIV
530
SGNRNLCYAN
540
TISWKKLFGT
550
ASQKTKIINN
560
RSEKECKAMG
570
HICNPLCSSE
580
GCWGPEPRDC
590
MSCRNFSRGK
600
ECVEKCNVLE
610
GEPREFVENA
620
ECVQCHPECL
630
PQAKNVTCMG
640
RGPDSCVRCA
650
HYIDGPHCVK
660
TCPAGIAGEN
670
STLIWKFADA
680
NHVCHLCHPN
690
CTYGCVGPGL
700
EGCAVDRPKI
710
PSIATGIVGG
720
LLLAVVLALG
730
VGLFLRRRHI
740
VRKRTLRRLL
750
QERELVEPLT
760
PSGEAPNQAL
770
LRILKETEFK
780
KVKVLGSGAF
790
GTVYKGLWIP
800
EGEKVKIPVA
810
IKELREATSP
820
KANKEILDEA
830
YVMASVDNPH
840
VCRLLGICLT
850
STVQLITQLM
860
PFGCLLDYVR
870
EHKDNIGSQH
880
LLNWCVQIAK
890
GMNYLEDRRL
900
VHRDLAARNV
910
LVKTPQHVKI
920
TDFGLAKLLG
930
AEEKEYHAEG
940
GKVPIKWLAL
950
ESILHRVYTH
960
QSDVWSYGVT
970
VWELMTFGSK
980
PYDGIPASEI
990
STVLEKGERL
1000
PQPPICTIDV
1010
YMIMVKCWMI
1020
DADSRPKFRE
1030
LIIEFSKMAR
1040
DPQRYLVIQG
1050
DERMHLPSPT
1060
DSNFYRALMD
1070
EEDMEDVVDA
1080
DEYLVPQQGF
1090
FHSPATSRTP
1100
LLSSLSATSS
1110
TPAVACVDRN
1120
GSYPLKEDSF
1130
LQRYSSDPTG
1140
ALTEDSLDDT
1150
FLPAPEYVNQ
1160
SVPKRPAGSV
1170
QNPVYHNQPL
1180
SAAPGRDPHY
1190
QNSHSNAVGN
1200
PEYLNTPRPA
1210
CINGGLDGPA
1220
FWAQTGSHQI
1230
NLDNPDYQQA
1240
FFPKEAKSNG
1250
ICKGPAAENA
1260
EYLRAAPASS
DLTGA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016323 | basolateral plasma membrane |
| Cellular Component | GO:0030054 | cell junction |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0031901 | early endosome membrane |
| Cellular Component | GO:0030139 | endocytic vesicle |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0097489 | multivesicular body, internal vesicle lumen |
| Cellular Component | GO:0031965 | nuclear membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0043235 | receptor complex |
| Cellular Component | GO:0032587 | ruffle membrane |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0048408 | epidermal growth factor binding |
| Molecular Function | GO:0005006 | epidermal growth factor receptor activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0019900 | kinase binding |
| Molecular Function | GO:0019903 | protein phosphatase binding |
| Molecular Function | GO:0030296 | protein tyrosine kinase activator activity |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0098609 | cell-cell adhesion |
| Biological Process | GO:0071230 | cellular response to amino acid stimulus |
| Biological Process | GO:0071392 | cellular response to estradiol stimulus |
| Biological Process | GO:0038134 | ERBB2-EGFR signaling pathway |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:1905208 | negative regulation of cardiocyte differentiation |
| Biological Process | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway |
| Biological Process | GO:0042177 | negative regulation of protein catabolic process |
| Biological Process | GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| Biological Process | GO:0030307 | positive regulation of cell growth |
| Biological Process | GO:0030335 | positive regulation of cell migration |
| Biological Process | GO:0045739 | positive regulation of DNA repair |
| Biological Process | GO:0045740 | positive regulation of DNA replication |
| Biological Process | GO:0050679 | positive regulation of epithelial cell proliferation |
| Biological Process | GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
| Biological Process | GO:0048146 | positive regulation of fibroblast proliferation |
| Biological Process | GO:1902895 | positive regulation of miRNA transcription |
| Biological Process | GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0042327 | positive regulation of phosphorylation |
| Biological Process | GO:0090037 | positive regulation of protein kinase C signaling |
| Biological Process | GO:1903078 | positive regulation of protein localization to plasma membrane |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0070141 | response to UV-A |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.