Search Results
Overview
| Uniprot ID | A0A5G2QCB4 |
|---|---|
| Protein Name | Glutathione reductase |
| Gene Name | GSR |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 291 | VLKYSQVKEVKKTSS |
| 432 | EAICKYGKENVKIYS |
| 94 | AAVVESHKLGGTCVN |
Function
Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol
Protein Sequence
10
MALLVWTLSA
20
SAGPSWRQAA
30
RAFSRFAPPP
40
TRPASVFPRA
50
MASRQESQPQ
60
CWPPARSVAT
70
SFDYLVIGGG
80
SGGLASARRA
90
AELGARAAVV
100
ESHKLGGTCV
110
NVGCVPKKVM
120
WNTAVHSEFM
130
HDHVDYGFQS
140
CESKFNWRVI
150
KEKRDAYVSR
160
LNTIYQNNLT
170
KSHIEIIHGH
180
AAFTSDPQPT
190
VEVNGKKYTA
200
PHILIATGGV
210
PSVPPESQIP
220
GESLSVFNSC
230
NPLLSCSRSV
240
IVGAGYIAVE
250
IAGILSALGS
260
KTSLMIRHDK
270
VLRSFDSIIS
280
SNCTEELENA
290
GIEVLKYSQV
300
KEVKKTSSGL
310
ELCMVTSVPG
320
RKPTFSTISG
330
VDCLLWAIGR
340
DPNSRGLNLS
350
QLGIQTDDKG
360
HIIVDEFQNT
370
NVKGIYAVGD
380
VCGRALLTPV
390
AIAAGRKLAH
400
RLFECKEDSK
410
LDYDNIPTVV
420
FSHPPIGTVG
430
LTEDEAICKY
440
GKENVKIYST
450
TFTPMYHAVT
460
KRKTKCVMKM
470
VCANKEEKVV
480
GIHMQGIGCD
490
EMLQGFAVAV
500
KMGATKSDFD
510
NTVAIHPTSS
EELVTLR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0050660 | flavin adenine dinucleotide binding |
| Molecular Function | GO:0004362 | glutathione-disulfide reductase (NADPH) activity |
| Molecular Function | GO:0050661 | NADP binding |
| Biological Process | GO:0045454 | cell redox homeostasis |
| Biological Process | GO:0006749 | glutathione metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.