Search Results

Overview

Uniprot ID	A0A5G2QCG3
Protein Name	UDP-glucose ceramide glucosyltransferase-like 1
Gene Name	UGGT2
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
1458	DESKQRAKTIDLCNN
1467	IDLCNNPKTKEPKLK

Function

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation

Protein Sequence

10 MAEAADAVRL 20 LLSSTALWLL 30 LLGAGTASAS 40 KAVTAHLTAK 50 WPETPLLLEA 60 SEFMAEESNE 70 KFWQFLETVQ 80 ELAIYKKTES 90 DYSYYNLILK 100 KAGQFLDNLH 110 INLLKFAFSI 120 RAYSPTVQMF 130 QQIAADEPPP 140 DGCDAFVVIH 150 KKHTCKINQI 160 KKLLKKATSR 170 PRPYLFKGDH 180 KFPTNRENLP 190 VIILYAEMGT 200 RAFRQFHTVL 210 SEKAQNGEIL 220 YVLRHYIQKP 230 ASQKMYLSGY 240 GVELAIKSTE 250 YKALDDTQVK 260 TVTNTSVEDK 270 TETNEVQGFL 280 FGKLKERYSD 290 LRDNLTTFQK 300 YLIESNKEMM 310 PLKVWELQDL 320 SFQAASQIKS 330 TPVYDAIKLM 340 KDISQNFPVK 350 ARSLTRIAVN 360 QHMREEIQEN 370 QKYLLDEFEI 380 QPGDAYLYIN 390 GLHIDIDSYD 400 PFSLLDMLKL 410 EGKLMNGLHS 420 LGINGEDMST 430 FLKLSSRGWE 440 DTYALDIRHS 450 SIMWINDLEN 460 DDLYASWPAS 470 CQELLKPVFP 480 GSIPLIRRNF 490 HNLVLFIDPA 500 QEYTLDFIKL 510 AELFYYHKIP 520 LRIGFVFIVN 530 TDDEVDGTND 540 AGVALWRAFN 550 YIAEEHGVSQ 560 AFISIVHMYE 570 KVKNKNILTV 580 DNVKSVLQDK 590 FPHANIWDIL 600 GVYSKYDDER 610 KAGANFYKMT 620 GLGPLPQALY 630 NGESFDGEEL 640 NVNELEVAVL 650 HRIMNVTKYL 660 QKEVFMGTLN 670 DETNAIDFLM 680 DKDNVVPRIN 690 PLILQSKWQY 700 LNLISTSVTA 710 DVEDFSTFLF 720 LDSQDKSAVI 730 AENMYYLTHE 740 DGDVISLVTF 750 WIIADFDKPS 760 GRKVLFNALE 770 HMETSVYSRL 780 GIIYNPTSKI 790 DEESTAISRG 800 ILAAFLTQRN 810 NFLRNFLMKL 820 TEEETATAIY 830 SGAKIKTFLT 840 EGMDKNAFEK 850 KYNTIGVNIF 860 RTHQLFCQEV 870 LKLNPGEIGV 880 VSNGKFLGPL 890 DDNFYAEDFY 900 LLEKITATNL 910 IDAIEDIVET 920 TEIDSEDLSD 930 LIMKIDALVS 940 SLPNHASRYD 950 VTFLKENHSI 960 IKINSQEEDM 970 VFDVIAIVDP 980 LTREAQKMAQ 990 LLIVLGKIIN 1000 MKIKLFMNCR 1010 GKLSEAPLKS 1020 FYRFVLEPEL 1030 TLTANDVAGP 1040 VAKFLDIPES 1050 PLLTLNMITP 1060 EGWLVETVHS 1070 NCDLDNIHLK 1080 DIERTVIAEY 1090 ELEYLLLEGH 1100 CFDITTEQPP 1110 RGLQFTLGTK 1120 NKPVMVDTIV 1130 MANLGYFQLK 1140 ANPGAWVLKL 1150 RQGKSEDIYQ 1160 IVGHKGTDSQ 1170 QERGDVVVVL 1180 NSFKSKILQV 1190 QVQKNPDRIK 1200 EDILSDKDGT 1210 KKGMWDSIKS 1220 FTKSLRKKDE 1230 KETDILNIFS 1240 VASGHLYERF 1250 LRIMMLSVLR 1260 NTKTPVKFWF 1270 LKNYLSPKFK 1280 EVIPHMAEEY 1290 GFQYELVQYR 1300 WPRWLHQQTE 1310 KQRIIWGYKI 1320 LFLDVLFPLA 1330 VDKIIFVDAD 1340 QIVRHDLKEL 1350 RDFDLGGAPY 1360 GYTPFCDSRR 1370 EMDGYRFWKT 1380 GYWASHLLRR 1390 KYHISALYVV 1400 DLKKFRKIAA 1410 GDRLRGQYQT 1420 LSQDPNSLSN 1430 LDQDLPNNMI 1440 YQVAIKSLPQ 1450 DWLWCETWCD 1460 DESKQRAKTI 1470 DLCNNPKTKE 1480 PKLKAAARIV 1490 PEWVEYDTEI 1500 RRLLDHLENK 1510 KKNAILTHDE L

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005788	endoplasmic reticulum lumen
Molecular Function	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process	GO:0009101	glycoprotein biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.