Search Results

Overview

Uniprot ID	A0A5G2QCS2
Protein Name	Long-chain-fatty-acid--CoA ligase
Gene Name	ACSL1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
394	IQSSLGGKVRLMVTG

Function

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation

Protein Sequence

10 MMQAHELFRY 20 FRMPELVDFQ 30 QYVRTLPTNT 40 LMGFGAFAAL 50 TTFWYATRPR 60 ALKPPCDLAM 70 QSVEVAGSDG 80 ARRSAILDSD 90 EPLAYFYDDV 100 RTLYEGFQRG 110 IRVSNNGPCL 120 GSRKPDQPYE 130 WLSYKQWVII 140 EQGCFAYSMV 150 VVPLYDTLGT 160 EAITYIINKG 170 ELSLVFVDKP 180 EKANLLLEGV 190 ENKLIPGLKT 200 IILMDSYGID 210 LLERGKKCGV 220 EIMSMKALED 230 LGRANRRKPK 240 PPAPEDLAVI 250 CFTSGTTGNP 260 KGAMITHRNV 270 VSDCSAFVKV 280 TEKTFSPSSD 290 DTLISFLPLA 300 HMFERVVECV 310 MLCHGAKIGF 320 FQGDIRLLMD 330 DLKALQPTIF 340 PVVPRLLNRM 350 FDRIFGQANT 360 TLKRWLLDFA 370 SKRKEAELRS 380 GIIRNNSLWD 390 KLIFHKIQSS 400 LGGKVRLMVT 410 GAAPVSATVL 420 TFLRAALGCQ 430 FYEGYGQTEC 440 TAGCSLTVPG 450 DWTAGHVGAP 460 MPCSLIKLVD 470 VEEMNYLAAK 480 GEGEVCVKGP 490 NVFQGYLKDP 500 AKTAEALDKD 510 GWLHTGDIGK 520 WLPNGTLKII 530 DRKKHIFKLA 540 QGEYIAPEKI 550 ENIYLRSEPV 560 AQVFVHGESL 570 QAFLIAIVVP 580 DVETLGHWAQ 590 KRGFVGSFEE 600 LCRNKDVKKA 610 ILEDMLRLGR 620 DAGLKSFEQV 630 RGISLHPELF 640 SIDNGLLTPT 650 MKAKRPELRN 660 YFRSQIDELY STVKV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0005741	mitochondrial outer membrane
Molecular Function	GO:0047676	arachidonate-CoA ligase activity
Molecular Function	GO:0005524	ATP binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.