Search Results
Overview
| Uniprot ID | A0A5G2QD62 |
|---|---|
| Protein Name | Mevalonate kinase |
| Gene Name | MVK |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 240 | TKVPRSTKALVASVR |
Function
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis
Protein Sequence
10
MLSQVLLVSA
20
PGKVILHGEH
30
SVVHGKVALA
40
VALNLRTFLR
50
LQPHNSGKVS
60
LRLPNIGIQQ
70
TWDVARLQLL
80
DTSFLEQGDL
90
TEQVEKLKEV
100
AGFSKDSTNH
110
DCLAVPAFLY
120
LYLTICRSQR
130
TLPSLDIAVW
140
SELPTGAGLG
150
SSAAYSVCLA
160
AALLTACEEI
170
PNPLKDGEAT
180
GRWTEENLEL
190
INKWAFQGER
200
VIHGNPSGVD
210
NAVSTWGGAL
220
RYQQGKISPL
230
KRLPTLEILL
240
VNTKVPRSTK
250
ALVASVRNRM
260
LKFPEIIAPL
270
LASMDAISLE
280
CERVLGEMAA
290
APALEHYLVL
300
EELIDMNQHH
310
LNALGVGHAS
320
LDQLCQVTTA
330
HGLHSKLTGA
340
GGGGCGITLL
350
RPDEHAEAQR
360
EKVTSPRPAS
WSTWQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004496 | mevalonate kinase activity |
| Biological Process | GO:0006695 | cholesterol biosynthetic process |
| Biological Process | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.