Search Results
Overview
| Uniprot ID | A0A5G2QEH9 |
|---|---|
| Protein Name | Thioredoxin-related transmembrane protein 2 |
| Gene Name | TMX2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 233 | LSGPCRYKVSTSPLT |
Function
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain
Protein Sequence
10
MAVLAPLIAL
20
IYSIPRLSRW
30
LARPYYLLSA
40
LLSAAFLLVR
50
KLPPVCYNLP
60
TQREDGNPCD
70
FDWREVEILM
80
FLSAIVMMKN
90
RRSITVEQHI
100
GNIFMFSKVA
110
NAILFFRLDI
120
RMGLLYLTLC
130
IVFLMTCKPP
140
LYMGPEYIKY
150
FSDKTIDEEL
160
ARDKRVTWIV
170
EFFANWSNDC
180
QSFAPIYADL
190
SLKYNCTGLN
200
FGKVDVGRYT
210
DVSTRYVGPG
220
SGITLSHVYR
230
YIHRVLSGPC
240
RYKVSTSPLT
250
KQLPTLILFQ
260
GGKEVMRRPQ
270
IDKKGRAVSW
280
TFSEENVIRE
290
FNLNELYHRA
300
KKVSKAGDNI
310
PEEEPIAQTP
320
TAAPDQESKK
DK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0044233 | mitochondria-associated endoplasmic reticulum membrane contact site |
| Cellular Component | GO:0031966 | mitochondrial membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0015036 | disulfide oxidoreductase activity |
| Biological Process | GO:0007420 | brain development |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.