Search Results

Overview

Uniprot IDA0A5G2QEZ2
Protein NameEukaryotic translation initiation factor 3 subunit B
Gene NameEIF3B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
186 KIFSKFGKITNDFYP
224 VKNADGYKLDKQHTF
227 ADGYKLDKQHTFRVN
315 TYVRWSPKGTYLATF
406 FKWSHDGKFFARMTL
433 LLDKKSLKISGIKDF
491 DCKLHWQKNGDYLCV
499 NGDYLCVKVDRTPKG
652 FQGRLLQKNSKDRFC
677 LLSQDQIKQIKKDLK
693 YSKIFEQKDRLSQSK
700 KDRLSQSKASKELVE
703 LSQSKASKELVERRR

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome

Protein Sequence

10 MQDAENVAAP 20 EASEQRAEPG 30 QQEPTAEAPP 40 REEPARPAAL 50 EGAGGEDPEA 60 GPGPDVPAEP 70 LADGEQKTDA 80 TPGASPPPSE 90 EPPTLAAGET 100 GQARDAAAEA 110 GSEGAGGEPG 120 GAAEDGGADE 130 PSFSDPEDFV 140 DDVSEEELLG 150 DVLKDRPQEA 160 DGIDSVIVVD 170 NVPQVGPDRL 180 EKLKNVIHKI 190 FSKFGKITND 200 FYPEEDGRTK 210 GYIFLEYAAP 220 AHALDAVKNA 230 DGYKLDKQHT 240 FRVNLFTDFD 250 KYMTISDEWD 260 IPEKQPFKDL 270 GNLRYWLEEA 280 ECRDQYSVIF 290 ESGDRTSIFW 300 NDVKDPVSIE 310 ERARWTETYV 320 RWSPKGTYLA 330 TFHQRGIALW 340 GGEKFKQIQR 350 FSHQGVQLID 360 FSPCERYLVT 370 FSPLMDTQDD 380 PQAIIIWDIL 390 TGQKKRGFHC 400 ESSAHWPIFK 410 WSHDGKFFAR 420 MTLDTLSIYE 430 TPSMGLLDKK 440 SLKISGIKDF 450 SWSPGGNIIA 460 FWVPEDKDIP 470 ARVTLMQLPS 480 RQEIRVRNLF 490 NVVDCKLHWQ 500 KNGDYLCVKV 510 DRTPKGTQVM 520 TCRAVCPVPM 530 SETIIAFAWE 540 PNGSKFAVLH 550 GEAPRISVSF 560 YHVKNNGKIE 570 LIKMFDKQQA 580 NTIFWSPQGQ 590 FVVLAGLRSM 600 NGALAFVDTS 610 DCTVMNIAEH 620 YMASDVEWDP 630 TGRYVVTSVS 640 WWSHKVDNAY 650 WLWTFQGRLL 660 QKNSKDRFCQ 670 LLWRPRPPTL 680 LSQDQIKQIK 690 KDLKKYSKIF 700 EQKDRLSQSK 710 ASKELVERRR 720 TMMEDFRKYR 730 KKAQELYMEQ 740 KNERLELRGG 750 VDTDELDSNV 760 DDWEEETIEF 770 FVTEEIIPLG NQE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0010494 cytoplasmic stress granule
Cellular Component GO:0016282 eukaryotic 43S preinitiation complex
Cellular Component GO:0033290 eukaryotic 48S preinitiation complex
Cellular Component GO:0005852 eukaryotic translation initiation factor 3 complex
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003743 translation initiation factor activity
Molecular Function GO:0031369 translation initiation factor binding
Biological Process GO:0001732 formation of cytoplasmic translation initiation complex

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.