Search Results
Overview
| Uniprot ID | A0A5G2QF04 |
|---|---|
| Protein Name | Amine oxidase [flavin-containing] A |
| Gene Name | MAOA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 109 | LVQYVKGKSYPFRGA |
| 223 | TNGGQERKFVGGSGQ |
| 377 | HKEIRKRKICELYAK |
| 470 | EILNALGKVSKKDIW |
| 87 | NRILRLSKELGLETY |
Function
Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially oxidizes serotonin. Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline
Protein Sequence
10
MNIKAEEKWP
20
LLRNKQEELG
30
EPTGINHSYR
40
LSAAKLLNEY
50
GINVLVLEAR
60
DRVGGRTYTV
70
RNENVDYVDV
80
GGAYVGPTQN
90
RILRLSKELG
100
LETYKVNVNE
110
CLVQYVKGKS
120
YPFRGAFPPV
130
WNPIAYLDYN
140
NLWRTMDDMG
150
KKIPADAPWE
160
SPHAEEWDKM
170
TMKDLIDKIC
180
WTKTAKRFAS
190
LFVNINVTSE
200
PHEVSALWFL
210
WYVKQCGGTT
220
RIFSVTNGGQ
230
ERKFVGGSGQ
240
VSERIMHLLG
250
DRVKLRCPVT
260
YVDQSGDNII
270
VETLNHELYE
280
CQYVISAIPP
290
TLTAKIHFRP
300
ELPSERNQLI
310
QRLPMGAIIK
320
CMMYYKEAFW
330
KKKNYCGCMI
340
IEDEEAPISI
350
TLDDTKPDGS
360
LPAIMGFILA
370
RKADRLAKVH
380
KEIRKRKICE
390
LYAKVLGSQE
400
ALHPVHYEEK
410
NWCEEQYSGG
420
CYTAYFPPGI
430
MTQYGRVIRQ
440
PVGRIFFAGT
450
ETATQWSGYM
460
EGAVEAGERA
470
AREILNALGK
480
VSKKDIWLRE
490
PESEDVPAFE
500
ITRTFWERNL
510
PSVTGLLKII
520
GFSTSVTALW
530
LAVYKFRLLT
RS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Molecular Function | GO:0097621 | monoamine oxidase activity |
| Molecular Function | GO:0008131 | primary methylamine oxidase activity |
| Biological Process | GO:0006584 | catecholamine metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.